AB Sciex API 4000 Triple Quad V-Series 

Available from KRSS a used fully refurbished and serviced AB-SCIEX API 4000 V-series triple quad mass spectrometer manufactured in 2008/2009. Price includes installation, training and 3 months warranty. 

API 4000 LC/MS/MS enhanced high performance triple quadruple mass spectrometer system is a high quality instrument with outstanding value. The API 4000 LC/MS/MS has a mass range of m/z 5 to 3000.

  • Overview
  • Features
  • Why purchase used refurbished
    mass specs from KRSS
  • Find Out More


The API 4000™ LC/MS/MS System established the standard of performance, reliability, and dependability for quantitative analysis.

  • Sensitive results for drug development
  • Robust, high-throughput efficiency
  • Low detection limits for trace analysis

    Even in complex matrices
    Whether you’re an expert or just getting started in LC/MS/MS, the API 4000 System makes it easy to get high-quality results, with outstanding quantitation and precise identification of low abundance compounds, even in matrices such as clinical samples, pesticide/drug residues, forensic toxicology samples, environmental samples,
    and foods.


    From the advanced Turbo V™ ion source, to the reliable interface, and the patented LINAC®
    collision cell, the API 4000™ ion path accelerates productivity.

    Plug-and-Play probes

    The Turbo V™ Source
    Effortless flexibility: Change quickly between APCI (atmospheric pressure chemical ionization) and TurboIonSpray® probes. Efficient ionization: Decrease chemical noise, enhance gas dynamics, and improve quantitation levels even at flow rates as high as 3 mL/min.

    Pristine ceramic interface
    Unparalleled ruggedness: Proven Curtain Gas™ interface technology combined with improved gas dynamics in the ion-source housing reduces maintenance and increases uptime.

    Rugged, reliable operation
    The innovative APCI probe reduces peak tailing from cross contamination and other sources of chemical noise. Absorptive residues are eliminated. So you reduce thermal degradation and ionization suppression, while increasing sensitivity and throughput even at flow rates up to 3 mL/min. The Turbo V source’s self-cleaning capability ensures uninterrupted, reproducible operation, and day-in, day-out reliability.

    Unique collision cell design
    The API 4000™ System uses patented LINAC® high-pressure collision cell technology to ensure maximum ion transfer from the interface to the detector. The LINAC collision cell enables fast scanning without compromising performance in all MS/MS modes, including multiple reaction monitoring (MRM), product ion scan, precursor ion scan, and neutral loss scan. For quantitative applications, the LINAC collision cell translates into multiple component analysis in a single-period MRM experiment. In qualitative applications, the LINAC collision cell enables faster precursor ion and neutral loss scans with excellent sensitivity and resolution.

    Dependable digital pulse-counting detector
    The sensitive pulse-counting detector in the API 4000 System provides consistent quantitative results over a wide dynamic range. Reproducible intra-day and inter-day results quickly validate even your most difficult assays.

    Greater sensitivity and ease-of-use make all the difference

    Advanced source design features highly efficient ionization probes.

    The Turbo V™ Source for the API 4000™ System maximizes ionization efficiency by combining embedded ceramic heater technology with improved gas dynamics. The increased ion yield in the gas phase translates into greater sensitivity. The dual heaters in the Turbo V Source provide greater efficiency in ionization over the wide range of liquid flow rates used in drug metabolism and pharmacokinetic (DMPK) analysis. Improved heat transfer and gas dynamics provide
    a tenfold increase in sensitivity.

    With the advanced Turbo V Source, you can switch between APCI and TurboIonSpray® probes in seconds. Determining the optimal ionization technique during method development is now simpler and faster.

    Higher sensitivity
    The TurboIonSpray probe increases sensitivity at flow rates up to 3 mL/min, without flow splitting.

    Higher throughput
    The Turbo V source virtually eliminates cross-contamination, even with large sample loads. Injection of 5-fluorouracil every 30 seconds demonstrates no discernible
    peak tailing.

    Why purchase used refurbished
    mass specs from KRSS

    KRSS Ltd offer high quality pre-owned Mass Spec, LCMS, GCMS, HPLC and GC systems allowing affordable entry into a rapidly developing market.

    All KRSS instruments are thoroughly inspected by manufacturer trained engineers (including all components and parts), cleaned and decontaminated, completely refurbished (defective parts and components are replaced with genuine parts), serviced and bench tested to ensure the equipment meets the manufacturers original specifications - this guarantees quality, performance and reliability at a fraction of the OEM costs.

    With over 50 instruments in stock, covering all major manufacturers KRSS has systems for a variety of application requirements. All instruments are supplied with a comprehensive warranty and optional service contracts to ensure trouble free operation.



    KRSS Left Strip