Agilent 1100 MSD

Available from KRSS a used fully refurbished Agilent 1100 MSD Model G1946D complete with Agilent 1100 HPLC system. Installation and 3 months warranty included (extended warranty available).

The Agilent 1100 Series LC/MSD is a benchtop mass spectrometer designed to be integrated with the 1100 Series HPLC System. It is a quadrupole based atmospheric pressure ionization (API) instrument capable of doing both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI). The LC/MSD can handle normal HPLC flow rates (<0.01 ml/min to >1 ml/min) without splitting the effluent and with minimal adjustment of the spray chamber.

  • Overview
  • 1100 Series MSD Advantage
  • Why purchase used refurbished
    mass specs from KRSS
  • Find Out More


Benchtop mass spectrometers have become the detector of choice in many applications of gas chromatography. This is particularly true for target compound identification in complex matrices or when the consequences of a false identification might involve litigation or other serious consequences. Now that small, simple-to-use benchtop mass spectrometers can be easily interfaced to liquid chromatographs, their use in HPLC applications is also becoming more prevalent.

Mass Range

  • 50-3000 m/z
  • Mass Accuracy

  • ±0.13 u
  • Mass Axis Stability

  • ±0.13 u over 8 hours
  • Scan Speed

  • 2500 u/s standard mode
  • 5250 u/s fast mode
  • SIM Sensitivity

    QuantitySignal-to-noise ratio
    1 pg50:1 RMS
    reserpine(10:1 peak-to-peak)

    1100 Series MSD Advantage

    The MSD instrument has no mechanical adjustments and all parameters affecting performance and data quality are under data system control. As has long been standard with Agilent Technologies GC/MSDs, an autotune algorithm is provided which automatically introduces a calibrant mixture and calibrates the mass axis as well as adjusting mass resolution and optimizing lens settings. As a result of this ease-of-use and ruggedness, it is ideally suited to be used by the chromatographer as an HPLC detector. At the same time, the LC/MSD has all the features and performance expected by the mass spectrometrist. Since the MSD relies on the formation, mass separation and detection of ions as its mode of operation rather than the absorbance of light, it is to be expected that its performance as a detector will be somewhat different than a diode array detector (DAD) or other UV detector.

    The 1100 Series LC/MSD offers many advantages as an LC detector. It offers the dynamic range and repeatability needed for most quantitative applications. In the SIM mode, it offers high sensitivity. For compounds lacking a strong chromophore, it offers detection limits not possible with other detectors. By offering unit mass resolution to m/z 3000, the LC/MSD allows for characterization of large proteins beyond 60,000 KDalton. Having extended mass range to 3000 is also beneficial when studying modified proteins such as glycoproteins where their charge distribution falls above m/z 2000. The added selectivity of mass information can allow for faster analysis times since baseline separation of individual components in a mixture is not required provided that they have different molecular weights. The added confidence provided by the presence of one or more unique ions at a specific retention time makes the LC/MSD the detector of choice when false positives would have serious consequences. This is especially true when used in conjunction with the iode array detector.

    Why purchase used refurbished
    mass specs from KRSS

    KRSS Ltd offer high quality pre-owned Mass Spec, LCMS, GCMS, HPLC and GC systems allowing affordable entry into a rapidly developing market.

    All KRSS instruments are thoroughly inspected by manufacturer trained engineers (including all components and parts), cleaned and decontaminated, completely refurbished (defective parts and components are replaced with genuine parts), serviced and bench tested to ensure the equipment meets the manufacturers original specifications - this guarantees quality, performance and reliability at a fraction of the OEM costs.

    With over 50 instruments in stock, covering all major manufacturers KRSS has systems for a variety of application requirements. All instruments are supplied with a comprehensive warranty and optional service contracts to ensure trouble free operation.


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