Thermo Q Exactive

Now available from KRSS, a used fully refurbished and serviced Thermo Q Eaxctive Hybrid Quadrupole-Orbitrap Mass Spectrometer with  Nano Spray Ion Source, 3 months warranty and installation.

  • Overview
  • Description
  • Specifications
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Overview

identify, quantify and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. This benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in drug discovery, proteomics, environmental and food safety, clinical research and forensic toxicology.

Description

High-Confidence Results, Quickly
  • HRAM and full-scan capabilities capture all sample data, all the time, enabling retrospective data analysis without need to re-run samples
  • Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices
  • Better than 1ppm mass accuracy in full-scan and all-ion fragmentation (AIF) modes ensures confident compound identification
  • Fast scanning at 12hz and spectral multiplexing suited to UHPLC applications
  • Rapid polarity switching maximizes information obtained
  • AIF and multiple dissociation techniques - in-source CID and HCD - aid in compound identification
  • Extended mass range to 6,000m/z enhances detection of singly charged small molecules and biomolecules
  • More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan

Greater Confidence for Drug Discovery and Metabolism Studies

  • Triple quadruple-equivalent ability to quantify parent compounds and metabolites along with identity confirmation provides greater throughput
  • Fast HRAM Orbitrap technology eliminates interferences for high-confidence metabolite structural identification and large-scale profiling of metabolomics and lipidomics samples
  • Fast scan-to-scan polarity switching in both MS and MS/MS modes maximizes metabolite detection and identification from a single injection

More Information for Superior Proteomics

  • HCD yields superior fragmentation and higher-quality MS/MS spectra compared to CID, improving identifications
  • High spectral quality and a wide dynamic range make it possible to identify and quantify proteins other instruments cannot find.
  • Quan/qual capability make it easier to transition from proteomic discovery experiments to targeted protein quantification

Highly Specific Environmental and Food Safety Analyses

  • Specificity exceeding triple quadruple Q-TOF or Q-Trap levels make this mass spectrometer the preferred quan/qual screening platform
  • Data-dependent, full-scan MS/MS capabilities and HRAM data ensure the highest possible confidence in every identification

High-Confidence Quanfirmation for Clinical Research and Forensic Toxicology

  • The combination of SRM and HRAM capabilities provides high-confidence quanfirmation of endogenous steroids, drugs of abuse and pain-management therapeutics with ease.

Application-Specific Software for Greater Throughput

  • Thermo Scientific™  ExactFinder™, LCQuan™, Mass Frontier™, MetQuest™, MetWorks™, SIEVE™ and TraceFinder™  software are available to speed data analysis.

Specifications

                                                                                                                                               
Mass Range50 to 6,000 m/z
Dynamic Range>5000:1
Mass AccuracyInternal: <1ppm RMS; External: <3ppm RMS
Polar SwitchingOne full cycle in <1 sec (one full positive mode scan and one full negative mode scan at a resolution setting of 35,000)
SensitivityFull MS: 500fg Buspirone on column S/N 100:1
SIM: 50 fg Buspirone on column yields S/N 100:1 or better
Resolution140,000 at m/z 200
Scan RatesUp to 12 Hz

Demo

 
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